Helicobacter pylori infection in peptic ulcer and gastric cancer diseases.

[Helicobacter pylori infection in peptic ulcer and gastric cancer diseases].

胃 お よ び 十 二 指 腸 潰 瘍 は消 化 性 潰 瘍 と呼 ば れ て お り,日 本 人 で は特 に 胃潰 瘍 の頻 度 が 高 い.そ の 原 因 と して 「no acid no ulcer」 と言 わ れ る よ う に,胃 酸 が そ の主 役 を つ とめ,ス トレ ス,非 ス テ ロ イ ド系 消 炎 鎮 痛 剤 な どが 発 生 の脇 役 を つ とめ る と理 解 され て きた.現 在 で も,H2-プ ロ ッカ ー,プ ロ トンポ ン プ ・有 ン ヒ ビ ター(PPDに 代 表 され る, 胃酸 分 泌 抑 制 剤 が 潰 瘍 治 療 の 中 心 で あ り,粘 膜 保 護 剤 で 潰 瘍 治 癒 を促 進 させ る と い う治 療 法 に は 変 わ りが な い.ま た,H2-プ ロ ッ カ ー の登 場 は 潰 瘍 外 科 治 療 を激 変 ...

Helicobacter pylori infection in peptic ulcer disease and gastric malignancy.

Helicobacter pylori infection is the world's most common chronic infection in humans and is the cause of most gastritis cases. This infection is accepted as the etiology of the majority of peptic ulcers. It has been implicated as a significant contributing factor in the development of gastric malignancy--both gastric MALT lymphoma and gastric adenocarcinoma. Both endoscopic and non-endoscopic t...

Helicobacter pylori, peptic ulcer and gastric cancer in China.

INTRODUCTION Recent epidemiological evidence supports a strong relationship between Helicobacter pylori infection and gastric cancer [1-11]. The relative risk for cancer with an infection of five years and over is in the region of three to six (Table 1). The identification of almost universal coexistence of H. pylori related antral gastritis in patients with duodenal ulcer disease [12, 13] and ...

[Helicobacter pylori infection in peptic ulcer disease].

Histological Changes In Gastric Biopsies From Helicobacter Pylori-Infected Patients With And Without Peptic Ulcer

  Background and Objective: Long period risk of gastric carcinoma in people affected with chronic Helicobacter pylori gastritis is 5 times more than normal people. Perhaps histological changes due to helicobacter pylori infection could be used for screening people at risk of gastric carcinoma and peptic ulcer. Materials and Methods: This study has been carried out as a cross...